Tempco Blog articles

Precise thermal control in pharmaceutical research

09/01/2026

Fine and accurate temperature regulation is a delicate and crucial element in pharmaceutical production. At the heart of a GMP (Good Manufacturing Practice)-certified cleanroom, a Tempco TREG thermoregulation unit supports a pilot reactor for the production of anticancer chemotherapy drugs.

The installed TREG manages a temperature range from –5° C to +90° C, using glycol water as monofluid heat transfer. The unit delivers 24 kW of power in both the heating and cooling phases, allowing for extremely precise modulation of the operating conditions of the reactor’s double shell, depending on the different phases of the drug production process.

Image showing a Tempco TREG temperature control unit for thermpregulation of reactors used in pharmaceutical research and chemotherapy drug production.

The full stainless steel construction and compact design facilitate cleaning and maintenance, ensuring full compliance with the sterile environment requirements of the pharmaceutical industry. Every detail, from components to electronics, is designed to offer reliability, repeatability, and safety in laboratory processes and small production batches for research activities of new active ingredients.

Image showing a Tempco TREG thermoregulation unit in full stainless steel construction for precise temperature control of reactors used in chemotherapy drug production.

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Best wishes from Tempco, Happy Holidays and a New Year 2026 full of energy!

23/12/2025

Tempco offices will be closed from Tuesday, December 23rd until January 6th included. However, you can stay in touch with us through our Chatbot, available 24/7 to answer all your enquiries and needs.

And this year again, we gladly take this opportunity to wish you Happy Holidays, a warm and Merry Christmas, and a New Year 2026 filled with… thermal Energy, green and sustainable as it can be.

Happy Holidays, from the entire Tempco team!

Image showing the Christmas Greetings 2025 screenshot with the Tempco AI Chatbot contact, which remains always available 24/7 for all customer’s enquiries.

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Scheduled service, a smart choice for the lifecycle of Tempco thermal machines

19/12/2025

Thermal systems often operate under continuous working conditions, with intense cycles and thermal load variations. Even the most robust unit, without scheduled maintenance, sees its performance decline over time: pumps lose efficiency, exchangers get dirty, valves derail from setpoints, and fluids get degraded with time and operations.

For this reason, we have been promoting the Tempco Service for years, a periodic maintenance program tailored specifically for our TREG thermoregulation units, cooling systems, thermoregulation skids, and custom control units.

The Tempco service specifically includes:

  • complete check of operating parameters;
  •  exchanger performance verification;
  • pump, valve, seal, and sensor inspection;
  • heat transfer fluid analysis and recommendation for replacement;
  • software updates and regulator calibration;
  • advance notification of components requiring replacement.

Image showing components of a temperature control unit, for which scheduled maintenance is essential for operational continuity.

 

The customer benefit is therefore very simple: zero surprises and maximum operations continuity. Scheduled maintenance allows also to:

  • avoid unexpected downtime;
  • keep energy consumption under control;
  • extend the life of your machines;
  • plan budgets and production downtime;
  • have priority access to our technical support.

Service also provides an opportunity to propose upgrades or new energy efficiency solutions, such as optimizing thermal cycles or introducing more efficient heat recovery systems.

At Tempco, we therefore don’t see maintenance as a ‘cost’, but rather as an investment to ensure that thermal machines perform exactly as they did on day one, along with the opportunity to continuously improve and optimize the operational efficiency of your thermal management and temperature control systems.

Image showing components of a Tempco TREG thermoregulation unit, for which scheduled maintenance is essential for the operational continuity of pumps, motors, and other components.

Image showing components of a thermoregulation unit, with a heat exchanger in the foreground, for which a maintenance program is the smartest choice.

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Efficiency and operational continuity: original spare parts make the difference

12/12/2025

Taking care of industrial production plants means choosing original spare parts, and this is a general rule. Specifically, in thermoregulation, cooling, and energy recovery systems, each component works in synergy with the others: pumps, valves, heat exchangers, heating elements, controls, sensors. Using an incorrect or uncertified spare part can seem like a minor detail… until the day the machine breaks down.

With original Tempco spare parts, however, the customer knows exactly what they’re installing, with the peace of mind of ensuring:

  • materials compatible with the process fluid;
  • guaranteed performance tested on our systems;
  • compliance with pressure and temperature specifications;
  • long-term reliability thanks to the selection of suppliers we’ve worked with for years.

Image showing some plates as original spare parts for heat exchangers, the choice of which is crucial to ensuring efficiency and operational continuity.

Image showing some gaskets as original spare parts for heat exchangers and thermal machine components, the choice of which is crucial to ensuring efficiency and operational continuity.

The difference, therefore, lies not only in the quality of the components themselves, but also directly impacts operational continuity: a correct gasket maintains the efficiency of the exchanger; a certified pump guarantees effective flow; consistent resistance prevents overheating or excessively frequent start-up cycles.

Furthermore, in a heating system, every deviation generates inefficiencies and hidden costs: higher energy consumption, longer rise/fall times in temperature, and micro-stoppages in production.

For all these reasons, at Tempco we always remind our customers that an original spare part costs less than a system downtime.

Tempco offers a dedicated service for the rapid supply of spare parts, even for older or custom-built machines. Keeping your systems in ideal condition thus means preserving their useful life, ensuring consistent performance.

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Precision and hygiene in stainless steel for pharma and food thermoregulation

05/12/2025

In critical sectors such as pharmaceuticals and food industry, precise temperature regulation and process hygiene are not just requirements, but fundamental pillars to guarantee product quality and safety. Tempco, thanks to its experience in industrial thermoregulation, has been meeting these needs for years for manufacturers in the pharmaceutical and food sectors with its range of T REG HC E thermoregulation units, which are now also available with an all-stainless steel frame, designed to raise standards in these sectors.

The choice to use stainless steel for the frame of our T REG HC E temperature control units is strategic, as it specifically meets the most stringent hygiene and durability requirements. This material guarantees excellent corrosion resistance, which is essential in environments requiring frequent cleaning and the use of sanitizing agents. Its smooth, non-porous surface prevents the accumulation of contaminants, making cleaning easier and ensuring superior sanitization, in full compliance with the stringent regulations to which the Pharma and Food sectors are subject.

Immagine che mostra una centralina di termoregolazione T REG HC E con struttura interamente in acciaio inox per elevati standard di precisione e igiene nei settori pharma e food.

T REG HC E control units are designed to deliver high-level performance, putting technology at the service of quality. They guarantee operating temperature precision of ±0.5°C thanks to advanced PID electronic control, essential for the stability and repeatability of production processes. Operating within a temperature range of +30° C to +300° C and managing fluids such as pressurized water (130°C) or diathermic oil (180°C or +300°C), they are suitable for a wide range of applications, from reactor heating to thermal control in pasteurization processes. Each component, from high-flow centrifugal pumps to high-efficiency plate heat exchangers, is selected to ensure reliability and consistent performance.

Immagine che mostra dettaglip del pannello di controllo di una centralina di termoregolazione T REG HC E con struttura interamente in acciaio inox per elevati standard di precisione e igiene nei settori pharma e food.

Immagine che mostra dettaglio del pannello di una centralina di termoregolazione T REG HC E con struttura interamente in acciaio inox per elevati standard di precisione e igiene nei settori pharma e food.

The applications of T REG HC E thermoregulation units are diverse, in addition to the customization options Tempco offers. Whether maintaining precise temperatures in mixing tanks or producing hot water for specific needs, the T REG HC E is the ideal solution. Tempco also offer a wide range of options upon request, allowing each unit to be customized with special pumps, increased cooling capacity, or communication interfaces for seamless integration into the user’s automation systems.

The Tempco T REG HC E stainless steel thermoregulation units are the perfect embodiment of Tempco’s commitment to offering cutting-edge temperature control solutions, combining precision with hygiene and reliability. Contact us to find out how our thermoregulation units can elevate the standards of your production processes in the pharmaceutical and food industries.

Immagine che mostra una centralina di termoregolazione T REG HC E con struttura interamente in acciaio inox per garantire elevati standard di precisione e igiene in applicazione nei settori pharma e food.

Immagine che mostra frontalmente una centralina di termoregolazione T REG HC E con struttura interamente in acciaio inox per garantire elevati standard di precisione e igiene in applicazione nei settori pharma e food.

Immagine che mostra una centralina di termoregolazione T REG HC E di Tempco con struttura interamente in acciaio inox per rispondere agli elevati requisiti di precisione e igiene nei settori alimentare e farmaceutico.

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PCHE exchanger for high-purity hydrogen compressors

28/11/2025

Tempco recently supplied a PCHE exchanger designed for installation on a hydrogen compressor, delivered to a major customer that manufactures alternative compressors employing highly innovative technologies and solutions for applications in compressed natural gas (CNG), biogas and biomethane production, and the hydrogen industry.

The customer’s machine is designed to compress pure hydrogen up to 450 bar g, with a special design optimized to ensure maximum performance, high gas purity, and structural integrity under extremely high-pressure operating conditions.

Immagine che mostra una unità integrata per la compressione di idrogeno a elevata purezza comprensiva di scambiatore PCHE

The unit therefore uses components suitable for gas contact and sealing systems compatible with hydrogen, designed to resist the typical effects of this gas, including permeation and material embrittlement.

A crucial equipment among the compressor’s integrated components is the PCHE printed circuit plate heat exchanger supplied by Tempco. Thanks to its high thermal transfer efficiency, multi-stream operations allowing to manage gas cooling during multi-phase hydrogen compression cycles, and structural resistance to extremely high pressures, it offers the reliability, operational safety, and high efficiency required by the customer’s specific application.

Immagine ripresa dall'alto che mostra una unità integrata per la compressione di idrogeno a elevata purezza comprensiva di scambiatore PCHE

Immagine che mostra lo scambiatore di calore PCHE realizzato da Tempco per installazione in compressore per idrogeno a elevata purezza

The unit is intended for a variety of applications, from green hydrogen, electrolysis, to high-pressure hydrogen storage and injection into the grid, transportation, and hydrogen refueling stations.

Immagine che mostra frontalmente una unità integrata per la compressione di idrogeno a elevata purezza comprensiva di scambiatore PCHE
Immagine che mostra la targa dati dello scambiatore PCHE di Tempco realizzato per installazione in un compressore di idrogeno ad alta purezza, che mostra i vari stream con le pressioni di progetto
Immagine che mostra la vista panoramica dall'alto una unità integrata per la compressione di idrogeno a elevata purezza comprensiva di scambiatore PCHE

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Tempering and thermoregulation: the secret behind crisp and shiny chocolate

21/11/2025

In chocolate production, after the cocoa bean roasting, refining, and conching production steps discussed in previous posts, tempering represents the true art of pastry making, and here too, precision and temperature control is essential.

During tempering, the chocolate is heated, cooled, and then reheated following a very precise thermal cycle (45°C, 27°C, and finally 31-32°C). This process is essential for stabilizing the cocoa butter crystals in their most stable form, which guarantees a shiny, crispy, and heat-resistant final product.

Immagine che illustra la fase di temperaggio del cioccolato, in cui le centraline di termoregolazione sono essenziali per garantire la croccantezza e lucentezza del prodotto finale

Here, once again, thermoregulation units play a crucial role, ensuring that each step occurs at the correct temperature and with optimal timing. Poorly executed tempering can cause aesthetic defects, such as dull surfaces or streaks, and compromise the chocolate’s consistency. Precise temperature control, on the other hand, allows for a visually appealing product that is pleasing to the palate.

In this sense, the tempering phase is truly the touch of class that makes the difference in chocolate production.

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Integrated cooling for emergency generators

14/11/2025

In emergency generators (UPS, Uninterruptible Power Supply), the proper management of the heat generated by the engine is crucial in order to ensure continuity of service and long-term reliability. When the engine starts operating, especially under full load, temperatures rise rapidly, and heat dissipation becomes a key task to ensure a reliable system operation.

In Tempco, we create complete cooling systems that combine all the components needed to dissipate the heat produced by the engine and the charge air in a single solution, offering the advantage of an integrated design. This approach ensures hydraulic compatibility, ease of installation, and efficient and coordinated operation of all components.

The cooling system consists of:
• HX1 – Jacket water exchanger, dedicated to the main engine circuit.
• HX2 – Supercharged air exchanger, to maintain the optimal intake air temperature.
• P1/P2 – Pumping unit, built on a skid complete with pumps, valves, instruments, and electrical control panel.
• RAD – Remote electric radiator, installed in an optimal position for ventilation and heat dissipation.
• VEXP – Expansion tank, equipped with radiator cap, sight glass, and minimum level switch, supplied for customer installation based on the system configuration.

The system architecture can be described as follows:

Raffreddamento integrato per gruppi elettrogeni d'emergenza

The combination of the jacket water and charge air cooling circuits allows to maintain a constant operating temperature of the engine, improving efficiency and reducing emergency start-up times.

Compared to traditional solutions, where components are supplied separately, the Tempco system ensures simplified system management, with sizing and integration tailored to the engine specifications and upon installation environmental conditions.

This engineering approach combines modularity, reliability, and operational readiness, ensuring stable and high-performance cooling for emergency generators, always ready to go into action when needed.

Immagine che mostra un elettroradiatore come componente di un sistema integrato per raffreddamento di gruppi elettrogeni di emergenza

Immagine che mostra un componente di un sistema integrato per raffreddamento di gruppi elettrogeni di emergenza

Immagine che mostra uno scambiatore di calore come componente di un sistema integrato per raffreddamento di gruppi elettrogeni di emergenza

Immagine che mostra un componente di un sistema integrato per raffreddamento di gruppi elettrogeni di emergenza

Immagine che mostra il gruppo di pompaggio come componente di un sistema integrato per raffreddamento di gruppi elettrogeni di emergenza

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Custom thermoregulation units for OEMs in the food & pharma sectors

07/11/2025

In the food and pharmaceutical sectors, reliability and cleanliness of the production process are essential. To meet the needs of companies operating in the food and pharma sectors, Tempco creates a series of custom-designed thermoregulation units for machine and plant manufacturers (OEMs) who need to precisely manage process water temperatures, ensuring stability and repeatability over time.

These compact units are designed with custom dimensions for integration into the customer’s machine structure. Each version is configured based on application specifications: electric heating with resistances from 3 to 24 kW, forced circulation via a submersible foot pump, and cooling via a submersible coil connected to an industrial water circuit or external chiller.

The circuit is atmospheric, with a stainless steel tank, designed to ensure maximum hygiene and ease of maintenance. The recommended operating temperature range is 0/75°C, ideal for washing, mixing, or thermal conditioning of process fluids.

Image of the datasheet of Tempco custom-built thermoregulating units for OEMs in the food and pharmaceutical sectors.

Versions for both the pharmaceutical and food & beverage sectors feature materials and components compatible with wash-down environments and, upon request, sanitary clamp or DIN connections. Versions with remote control options via PLC, analogic signals, or fieldbus (Modbus, Profinet, EtherNet/IP) are also available.

These solutions offer OEMs the ability to easily integrate a complete, compact, and reliable thermoregulation system, reducing development times and ensuring an efficient thermal management of the production process. As always, each project begins with a technical consultation with the customer, to tailor dimensions, materials, power, and control logic to the specific needs of the system.

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PCHE, a turnkey solution for hydrogen refueling stations

31/10/2025

The image shows a PCHE heat exchanger for cooling applications at hydrogen refueling stations.

Hydrogen is becoming one of the most promising solutions for a sustainable energy future. Refueling hydrogen vehicles requires precise temperature management to ensure safety and efficiency. PCHE heat exchangers offer an innovative and reliable solution to these needs.

Hydrogen refueling is challenging for a number of reasons: hydrogen must be compressed to extremely high pressures (up to 700 bar) to be stored in vehicle tanks. During this process, a lot of heat is generated; if it is not managed, refueling becomes slower and less efficient. This is where PCHE heat exchangers technology can be applied.

Several characteristics make PCHE exchangers so special, ideal to solve the challenges posed by hydrogen technologies. What are PCHEs? Imagine a compact and robust device capable of rapidly cooling fluids. Their usefulness in hydrogen applications has several aspects:

  • They easily handle high pressures.
  • They are small, so they take up less space at refueling stations.
  • They cool the hydrogen quickly and precisely, speeding up the refueling process.

L'immagine mostra uno scambiatore di calore PCHE per applicazioni di raffreddamento nelle stazioni di rifornimento idrogeno

In the specific case of hydrogen refueling stations, the operation of PCHEs therefore adds value to a series of crucial steps to ensure the system’s efficiency and operational safety:

  • During refueling, the hydrogen is compressed and then cooled by the PCHEs before entering the vehicle’s tanks.
  • This process prevents the gas from overheating, making the process safer and faster.
  • Simply put, PCHEs help refueling stations operate more efficiently, allowing drivers to refuel in just a few minutes.

To give a practical example, a refueling station equipped with PCHEs can refuel more vehicles in less time. This brings a series of key advantages:

  • Time savings: less waiting time at the refueling station.
  • Improved reliability: the system does not overheat and always operates at its best.
  • Reduced operating costs, thanks to their energy efficiency.

Looking to the future of green mobility, the rise of hydrogen vehicles requires increasingly efficient refueling stations. PCHEs will be a key enabler of this growth, as their unique technology offers the ideal solution to overcome the challenges of hydrogen refueling. Thanks to their efficiency and reliability, they represent an investment in a greener and more sustainable future.

Find out how Tempco can support the growth of the hydrogen industry with dedicated innovative solutions. Contact us for a consultation or visit our dedicated website https://pche.it/en/.

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TEMPCO researches and develops systems and solutions for cooling, heating, control temperature and heat exchange in different industrial processes.

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